Phosphine-catalyzed dearomatizing [3+2] annulations of isoquinolinium methylides with allenes.
نویسندگان
چکیده
A phosphine-catalyzed dearomatizing [3+2] annulation of isoquinolinium methylides with allenoates or allenones yields highly functionalized pyrroloisoquinolines with high regioselectivity and in viable yields.
منابع مشابه
Nucleophilic Chiral Phosphines: Powerful and Versatile Catalysts for Asymmetric Annulations.
Recent advances in chiral-phosphine-catalyzed asymmetric annulation reactions; including annulations of allenes, alkynes, Morita-Baylis-Hillman (MBH) carbonates, and ketenes; and their applications in the synthesis of bioactive molecules and natural products are reviewed.
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 6 شماره
صفحات -
تاریخ انتشار 2015